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Updated: Aug 10, 2026

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
Powder diffraction study of the hydrogen bonds in nitroxoline and its hydrochloride
A V Yatsenko1, K A Paseshnichenko, V V Chernyshev
1Chemistry Department, Moscow State University, 119899 Moscow, Russia. yatsenko@biocryst.phys.msu.su
Abstract:
The crystal structures of 8-hydroxy-5-nitroquinoline, C9H6N2O3, (I), and 8-hydroxy-5-nitroquinolinium chloride, C9H7N2O3+*Cl-, (II), have been determined from X-ray powder data. In (I), the molecules are linked via moderately strong hydrogen bonds to form dimers. Such a packing motif is likely to be responsible for the low solubility of (I) in water. In (II), the inversion-related cations form stacks, and anions fill the interstack channels.
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