Related Experiment Video
Updated: Oct 3, 2026

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
Published on: April 13, 2022
New human teeth from Middle Stone Age deposits at Klasies River, South Africa
1Department of Anthropology, Binghamton University, SUNY, Binghamton, New York 13902-6000, USA. gpright@binghamton.edu
Abstract:
Since 1984, the main site at Klasies River has been re-investigated. Human remains, animal bones and stone artefacts have been collected from the LBS, SAS and other stratigraphic members, and these discoveries help to establish the antiquity of anatomically near-modern populations practicing a Middle Stone Age way of life on the southern coast of Africa. Several teeth found in the lower SAS levels in 1989-1991 can be matched in recent South African populations. Two complete upper molars representing one individual have crowns that are relatively short mesiodistally. These specimens are small in comparison to black South African homologues, but MD and BL dimensions fall close to the averages for San burials. This evidence confirms that several of the Klasies individuals have very small molars, while others have cheek teeth that are close to the upper limits for size variation in recent Africans. The new material is in keeping with the view that sex dimorphism within this Middle Stone Age population may be pronounced.
Related Concept Videos
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Fossil Record

