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[Clinical analysis of idiopathic thrombocytopenic purpura with pregnancy]
1Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Objective:
To study the optimal management of pregnant women with idiopathic thrombocytopenic purpura (ITP).
Methods:
The outcomes of 37 pregnancies with ITP about 10 years from (1990 to 1999) were analysed.
Results:
Among the 37 cases, vaginal delivery and cesarean section were done in 16 and 21 cases respectively. Neonatal thrombocytopenia was diagnosed in 3 newborns. None of them had intracranial hemorrhage. The incidences of postpartum hemorrhage and infection were 8.1% and 2.7%, respectively. No maternal mortality was noted.
Conclusions:
In view of very low morbidity in babies of ITP mothers, we suggest that they be delivered vaginally if there is no obstetrical complications. Selected cesarean delivery should be performed in severely thrombocytopenic cases when there are sufficient fresh blood and platelet. The invasive interventions should not be used to avoid newborn thrombocytopenia.
