Related Experiment Videos
Thioglycosides protected as trans-2,3-cyclic carbonates in chemoselective glycosylations
1Complex Carbohydrate Research Center, The University of Georgia, 220 Riverbend Road, Athens, GA 30602, USA.
Organic Letters
|January 11, 2002
Abstract:
Thioglycosides protected as trans-2,3-cyclic carbonates have significantly lower anomeric reactivities than fully acylated and N-acyl-protected thioglycosides and can be used as acceptors in chemoselective glycosylations with a wide range of thioglycosyl donors. The resulting thioglycosides can be further activated to give 1,2-cis-linked glycosides. [reaction: see text]