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Updated: Aug 1, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
The first atisane diterpenoids from a liverwort: polyols from Lepidolaena clavigera
N B Perry1, E J Burgess, S H Baek
1Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd., Department of Chemistry, University of Otago, Box 56, Dunedin, New Zealand. perryn@crop.cri.nz
Abstract:
Two new diterpenoids were isolated from the New Zealand liverwort Lepidolaena clavigera. Spectroscopic studies identified the structures as atisanes 1 and 2, with an unprecedented level of oxygenation. This is the first report of the atisane skeleton from a liverwort. Compound 2 showed cytotoxic and insecticidal activity. [structure: see text]
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