Related Experiment Video
Updated: Jan 25, 2026
Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
Salvage surgery for recurrent nasopharyngeal carcinoma
Sheng-Po Hao1, Ngan-Ming Tsang, Chen-Nen Chang
1Department of Otolaryngology, Chang Gung Memorial Hospital, Chang Gung University, Taoyua, Taiwan, Republic of China. shengpo@adm.cgmh.org.tw
Objective:
To evaluate the results of salvage surgery for patients with primary recurrence of nasopharyngeal carcinoma after radiotherapy.
Design:
Cohort study.
Setting:
Academic tertiary referral center.
Patients:
Eighteen consecutive patients with primary recurrence of nasopharyngeal carcinoma after radiation failure underwent nasopharyngectomy for cure via a facial translocation approach from July 1, 1993, to December 31, 1999. Follow-up ranged from 3 to 71 months. Five patients with skull base invasion required a combined neurosurgical approach to treatment. Seven patients had additional postoperative radiotherapy.
Results:
The actuarial 3-year survival was 57%, while the local control was 78%. Four of 5 patients who had skull base invasion achieved local control. There was no surgical mortality, and the morbidity was 22%.
Conclusion:
Advances in skull base surgery make possible the effective control of primary recurrence of nasopharyngeal carcinoma, with acceptable mortality and morbidity.
Related Concept Videos
01:29Suctioning the Nasopharyngeal Airway
Equipment Required
02:35Chromatin Position Affects Gene Expression
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...