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[Intracranial ependymomas].

M Gelabert González1, A García Allut, J M Fernández Villa

  • 1Servicio de Neurocirugía.Dpto. de Cirugía; Hospital General de Galicia, Santiago de Compostela, 15705, España. cimigego@usc.es

Revista De Neurologia
|January 11, 2002
PubMed
Summary
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Intracranial ependymomas, tumors of the central nervous system, are most effectively treated with complete surgical removal. Patient survival depends on tumor grade, surgical extent, and age.

Area of Science:

  • Neuro-oncology
  • Pediatric neurosurgery
  • Central nervous system tumors

Context:

  • Ependymomas are neuroepithelial tumors arising from ependymal cells.
  • Intracranial ependymomas represent 2-6% of central nervous system neoplasms.
  • Half of cases occur in individuals under 20 years old.

Purpose:

  • To review the epidemiology, clinical presentation, neuropathology, neuroradiology, and treatment of intracranial ependymomas.
  • To synthesize current knowledge on managing these CNS tumors.

Summary:

  • Posterior fossa ependymomas are more common in children; supratentorial tumors are more frequent in adults.
  • Complete tumor resection is the primary treatment modality.
  • Histological grade, extent of surgical removal, and patient age significantly influence postoperative survival.

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Impact:

  • Highlights the importance of maximal safe surgical resection for improving outcomes in intracranial ependymomas.
  • Provides a comprehensive overview for clinicians managing pediatric and adult patients with these tumors.
  • Emphasizes the prognostic factors critical for patient management and counseling.