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Updated: Oct 3, 2026
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
[Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats]
G B Pliss1, A S Mel'nikov, V V Malinin
1N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF, St. Petersburg.
Abstract:
Experimental data on the effect of peptides--Vilon (Lys-Glu) and Epitalon (Ala-Glu-Asp-Gly)--on induction of urinary bladder tumors in rats are presented. Treatment with Vilon was followed by a significant fall in tumor incidence in 56% of experimental animals, as compared with 75.5% in control, as well as inhibition of early-onset neoplastic changes in the bladder mucosa. No inhibitory effect of Epitalon was recorded.
