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Updated: Feb 27, 2026

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling
Published on: October 21, 2018
[Reorganization of the strain's cellular lipids--degradation of anionic surfactants during "detergent" stress]
S S Stavskaia1, I A Krivets, N I Nastoiashchaia
1National Technical University of Ukraine, Scientific-Research Institute of Epidemiology and Infectious Diseases, Ministry of Public Health of Ukraine, Kyiv.
Abstract:
Changes in the fatty acid composition and ultrastructure of Pseudomonas aeruginosa 1C strain--a destructor of alkyl sulphates under the effect of the stress evoked by sodium dodecyl-sulphate have been studied. It has been established that the "detergent" stress changes the ratio of the cell fatty acids (FA) towards the increase of their nonsaturation. Ultrastructural changes in the cells are revealed earlier than biochemical ones. Several stages in stress development have been distinguished. The escape from the stress state is performed both at the population level and at the level of individual cells, highly-resistant to dodecyl sulphate.
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