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Related Experiment Videos

Finasteride. Does it affect spermatogenesis and pregnancy?

M Pole1, G Koren

  • 1Hospital for Sick Children, Toronto, Ont.

Canadian Family Physician Medecin De Famille Canadien
|January 12, 2002
PubMed
Summary

Partners taking finasteride for male pattern baldness pose no risk to pregnant partners or fetuses. Handling finasteride tablets is unlikely to cause fetal exposure or harm, so discontinuation is unnecessary.

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Area of Science:

  • Pharmacology
  • Reproductive Health
  • Teratology

Background:

  • Concerns exist regarding potential risks of finasteride exposure during pregnancy, particularly to male fetuses.
  • Product monographs suggest even handling the medication could be harmful.

Purpose of the Study:

  • To assess the safety of finasteride use by male partners during a partner's pregnancy.
  • To determine the risk of fetal harm from accidental exposure to finasteride tablets.

Main Methods:

  • Review of existing literature and case reports.
  • Monitoring of pregnant women whose partners are taking finasteride.
  • Assessment of finasteride's effects on male semen parameters.

Main Results:

  • No adverse pregnancy outcomes have been reported in women exposed to finasteride.
  • Daily 1 mg finasteride dosage showed no clinically significant impact on male semen.
  • Transdermal absorption from handling tablets is highly unlikely to result in fetal exposure or harm.

Conclusions:

  • There is no evidence to suggest that finasteride poses a risk to pregnancy.
  • Men can continue taking finasteride while their partners are pregnant or planning pregnancy.
  • Continued monitoring of exposed pregnancies is underway.

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