Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Estrogen replacement therapy: a perspective on cognitive impact.

L J Tivis1, S J Nixon, M D Green

  • 1Department of Psychiatry and Behavioral Studies, Oklahoma Center for Alcohol and Drug-Related Studies, University of Oklahoma Health Sciences Center, Oklahoma City 73104, USA. Laura-Tivis@ouhsc.edu

Assessment
|January 12, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dementia and Its Profound Impact on Family Members and Partners: A Large UK Cross-Sectional Study.

Alzheimer disease and associated disorders·2024
Same author

Measurement of the major ignored burden of multiple myeloma, pernicious anaemia and of other haematological conditions on partners and family members: A cross-sectional study.

European journal of haematology·2024
Same author

Responsiveness and minimal important change of the Family Reported Outcome Measure (FROM-16).

Journal of patient-reported outcomes·2024
Same author

Mapping of Family Reported Outcome Measure (FROM-16) scores to EQ-5D: algorithm to calculate utility values.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation·2024
Same author

Baseline brain function in the preadolescents of the ABCD Study.

Nature neuroscience·2021
Same author

Adolescent neurocognitive development and impacts of substance use: Overview of the adolescent brain cognitive development (ABCD) baseline neurocognition battery.

Developmental cognitive neuroscience·2018

Estrogen replacement therapy (ERT) may not improve memory and concentration in postmenopausal women. Alcohol consumption interacts with ERT, suggesting it may explain some cognitive differences previously attributed to ERT.

Area of Science:

  • Neuroscience
  • Gerontology
  • Endocrinology

Background:

  • Estrogen replacement therapy (ERT) is suggested to preserve cognitive function post-menopause.
  • Potential confounding factors, like alcohol consumption, are often not systematically evaluated.
  • Understanding these interactions is crucial for accurate cognitive health assessments.

Purpose of the Study:

  • To investigate differences in memory and concentration between ERT users and non-users.
  • To examine the influence of alcohol consumption as a confounding variable.
  • To explore potential interactions between ERT and alcohol on cognitive performance.

Main Methods:

  • 162 postmenopausal women were classified as moderate drinkers or teetotalers.
  • Cognitive abilities were assessed using Logical Memory, Digit Span, and the Cognitive Symptom Checklist-Memory subscale.

Related Experiment Videos

  • Estrogen replacement therapy (ERT) use and alcohol consumption were independent variables.

    • Main Results:

    • No significant main effects of ERT on cognitive functioning were observed.
    • Significant interactions between ERT use and alcohol consumption were found for specific Digit Span Forward variables.
    • These findings indicate a complex relationship between ERT, alcohol, and cognition.

    Conclusions:

    • Cognitive differences attributed to ERT may be influenced by confounding variables like alcohol consumption.
    • Alcohol intake should be considered when evaluating the cognitive effects of ERT.
    • Further research is needed to elucidate the interplay between hormonal therapy, lifestyle factors, and cognitive health in aging women.