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Updated: Jul 11, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
Published on: July 4, 2016
Pulsed electron paramagnetic resonance methods for macromolecular structure determination
1Department of Chemistry, Yale University, New Haven, CT 06520, USA. k.lakshmi@yale.edu
Abstract:
Pulsed electron paramagnetic resonance (EPR) distance measurement techniques target macromolecular structure elucidation at both the local and global level. Recent developments in pulse microwave technology and high-field EPR have led to the development of a variety of pulsed EPR distance measurement techniques. These methods have emerged as powerful tools for the determination of structure/function relationships in macromolecular systems. In this review article, we discuss recent applications of long-range and short-range EPR distance measurements.
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