Aging alters the apoptotic response to genotoxic stress

Somatic mutations and genome mosaicism in aging and disease.

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Direct probabilistic quantification of mosaic loss of chromosome Y from sequencing data.

bioRxiv : the preprint server for biology·2026

Mutagen-induced somatic mutation rate in primary mammalian cells in relation to maximum life span.

Geromedicine·2026

The aging genome exhibits organized vulnerability to somatic mutations.

bioRxiv : the preprint server for biology·2026

Evidence for negative selection against somatic mutations induced in normal fibroblasts by N-ethyl-N-nitrosourea.

Genome research·2026

High cancer-associated mutational burden in normal blood of xeroderma pigmentosum group C, but not groups A, D, or F.

Blood neoplasia·2026

Large-scale AI-guided liver malignancy diagnosis: multicenter study and a single-arm trial.

Nature medicine·2026

Intramyocardial injection of allogeneic human induced pluripotent stem cell-derived cardiomyocytes in advanced ischemic heart failure: an early-stage randomized trial.

Nature medicine·2026

Prospective evaluation of a large language model clinical decision support system in the emergency department.

Nature medicine·2026

Traumatic brain injury outcomes across human development index strata in 29 countries.

Nature medicine·2026

County, district and community-level measles transmission in the United States in 2013-2025.

Nature medicine·2026

Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda.

Nature medicine·2026

Eco-evolutionary feedbacks generate bistability in population persistence under gradual environmental change.

bioRxiv : the preprint server for biology·2026

Structural divergence in protein evolution of a photoreceptor family undetected by AlphaFold is observed by high sensitivity FT-IR spectroscopy.

bioRxiv : the preprint server for biology·2026

Cross-species neural co-culture uncovers metabolic signatures of cellular crosstalk.

bioRxiv : the preprint server for biology·2026

Dose-dependent effects of recombinant spike protein-based vaccination on SARS-CoV-2 evolutionary dynamics and the emergence of variants in hamster models.

The Journal of general virology·2026

Molecular Mechanisms of Hypoxia-Driven Scleral Remodeling in Myopia Progression.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics·2026

Fitness effects of local seasonal adaptation depend on the timing of reproduction in a range-expanding butterfly.

Proceedings. Biological sciences·2026

Related Experiment Videos

Aging alters the apoptotic response to genotoxic stress

Related Concept Videos

Somatic mutations and genome mosaicism in aging and disease.

Direct probabilistic quantification of mosaic loss of chromosome Y from sequencing data.

Mutagen-induced somatic mutation rate in primary mammalian cells in relation to maximum life span.

The aging genome exhibits organized vulnerability to somatic mutations.

Evidence for negative selection against somatic mutations induced in normal fibroblasts by N-ethyl-N-nitrosourea.

High cancer-associated mutational burden in normal blood of xeroderma pigmentosum group C, but not groups A, D, or F.

Large-scale AI-guided liver malignancy diagnosis: multicenter study and a single-arm trial.

Intramyocardial injection of allogeneic human induced pluripotent stem cell-derived cardiomyocytes in advanced ischemic heart failure: an early-stage randomized trial.

Prospective evaluation of a large language model clinical decision support system in the emergency department.

Traumatic brain injury outcomes across human development index strata in 29 countries.

County, district and community-level measles transmission in the United States in 2013-2025.

Emergence and spread of Plasmodium falciparum PX1 polymorphisms associated with decreased susceptibility to antimalarials in Uganda.

Eco-evolutionary feedbacks generate bistability in population persistence under gradual environmental change.

Structural divergence in protein evolution of a photoreceptor family undetected by AlphaFold is observed by high sensitivity FT-IR spectroscopy.

Cross-species neural co-culture uncovers metabolic signatures of cellular crosstalk.

Dose-dependent effects of recombinant spike protein-based vaccination on SARS-CoV-2 evolutionary dynamics and the emergence of variants in hamster models.

Molecular Mechanisms of Hypoxia-Driven Scleral Remodeling in Myopia Progression.

Fitness effects of local seasonal adaptation depend on the timing of reproduction in a range-expanding butterfly.

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Aging alters the apoptotic response to genotoxic stress

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