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Related Experiment Videos

[Spasticity and multiple sclerosis].

B Bussel1, O R Neris, L Mailhan

  • 1Service de rééducation neurologique, Hôpital R. Poincaré, 92380 Garches.

Revue Neurologique
|January 15, 2002
PubMed
Summary
This summary is machine-generated.

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Spasticity in multiple sclerosis (MS) is common, but assessing functional disability and treatment benefits is challenging. Temporary therapeutic interventions are recommended for evaluating spasticity management in MS patients.

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Clinical Therapeutics

Context:

  • Spasticity is a frequent and challenging symptom for patients with multiple sclerosis (MS).
  • While spasticity at rest is easily evaluated, assessing functional disability and treatment efficacy in MS patients remains difficult.
  • Current treatment options for MS-related spasticity have documented efficacy, but functional outcome measurement is complex.

Purpose:

  • To highlight the difficulties in assessing functional disability and treatment benefits of spasticity in MS patients.
  • To propose the use of temporary therapeutic interventions as a more appropriate method for evaluating treatment efficacy.
  • To guide clinicians in selecting appropriate diagnostic and therapeutic strategies for MS spasticity.

Summary:

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  • Recognizing and evaluating resting spasticity in MS is straightforward, with many treatments showing efficacy.
  • Assessing the functional impact of spasticity and the benefits of interventions in MS patients presents significant challenges.
  • Therapeutic tests with transient effects, like anesthetic blocks for focal spasticity or intrathecal baclofen for diffuse spasticity, are suggested.
  • Reversible treatments, such as botulinum toxin injections, are also viable options before considering irreversible procedures like peripheral nerve section.

    • Impact:

    • Provides a framework for more accurate functional assessment in MS spasticity management.
    • Suggests a pragmatic approach to guide treatment decisions, potentially improving patient outcomes.
    • Emphasizes the importance of temporary interventions for evaluating the effectiveness of spasticity treatments in MS.
    • Aims to reduce the gap between documented treatment efficacy and observed functional improvement in MS patients.