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Related Experiment Videos

Isolated neonatal ductus arteriosus aneurysm.

Sheng-Ling Jan1, Betau Hwang, Yun-Ching Fu

  • 1Division of Pediatric Cardiology, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan. sljan@vghtc.vghtc.gov.tw

Journal of the American College of Cardiology
|January 15, 2002
PubMed
Summary

Ductus arteriosus aneurysm (DAA) is more common in full-term neonates than previously thought and typically resolves spontaneously. This study found a higher incidence of DAA with a good outcome, suggesting it may be a normal variant.

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Area of Science:

  • Neonatal Cardiology
  • Pediatric Echocardiography
  • Congenital Heart Abnormalities

Background:

  • Ductus arteriosus aneurysm (DAA) is considered a rare and potentially fatal congenital abnormality.
  • Previous reports suggest a low incidence and significant risks associated with DAA.

Purpose of the Study:

  • To evaluate the incidence, clinical manifestations, and outcome of ductus arteriosus aneurysm (DAA) in full-term neonates.
  • To determine if DAA represents a significant pathology or a normal variant in this population.

Main Methods:

  • Prospective echocardiographic screening of 548 full-term neonates.
  • Detailed analysis of DAA size, clinical presentation, and follow-up assessments.

Main Results:

Related Experiment Videos

  • Echocardiography detected DAA in 8.8% of neonates, with asymptomatic cases.
  • Newborns with DAA showed higher birth weight, maternal gestational diabetes, and maternal blood group A.
  • All identified DAAs resolved spontaneously within one month, with or without thrombus formation.

    • Conclusions:

    • The incidence of DAA in full-term neonates is higher than previously reported, with a favorable outcome.
    • DAA may represent a normal variant of the ductal bump and a component of spontaneous ductal closure.
    • Findings challenge the notion of DAA as a solely fatal abnormality.