Metabolic modulation: a means to mend a broken heart

Loss of SIRT2 in cardiomyocytes reduces glycolytic flux via increased acetylation of glycolytic enzymes.

American journal of physiology. Heart and circulatory physiology·2026

Lowering Cardiac Branched-Chain Keto Acid Levels Enhances Cardiac Glucose Oxidation and Cardiac Efficiency via Enhancing Mitochondrial Insulin Signaling in Heart Failure.

Circulation. Heart failure·2025

Casein Kinase 2α Ablation Confers Protection Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Role of FUN14 Domain Containing 1-Dependent Regulation of Mitophagy and Ferroptosis.

MedComm·2025

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC.

European journal of heart failure·2025

Sweeteners: erythritol, xylitol and cardiovascular risk-friend or foe?

Cardiovascular research·2025

Alterations of myocardial ketone metabolism in heart failure with preserved ejection fraction (HFpEF).

ESC heart failure·2025

Mechanosensitive Endothelial METTL7A Regulates Internal m7G mRNA Methylation and Protects Against Atherosclerosis.

Circulation·2026

YAP Promotes Microtubule Growth to Facilitate Sarcomere Disassembly in Adult Cardiomyocytes.

Circulation·2026

The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning.

Circulation·2026

ABHD11-Mediated mtDNA Transcription Restored Mitochondrial Function to Attenuate Cardiomyocyte Ferroptosis After Myocardial Infarction.

Circulation·2026

Opportunistic Screening for Chagas Disease Using an Artificial Intelligence-Enabled ECG: Prospective Evaluation of Feasibility and Diagnostic Accuracy.

Circulation·2026

The Postcardiac Arrest Inflammatory Response: Mechanisms and Therapeutic Targets.

Circulation·2026

Activation of a TFAM-Dependent Mitochondrial Translational Axis Drives Oxidative Metabolism in Grade 2 Meningiomas.

Cell biochemistry and function·2026

Targeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in rats.

iScience·2026

Diaphragmatic Eventration Masquerading as Lobar Collapse in Severe ABPA.

Respirology case reports·2026

Improvement of Severe Volume Dependent Airway Closure With Tezepelumab: A Case Report.

Clinical case reports·2026

Related Experiment Videos

Metabolic modulation: a means to mend a broken heart

Related Concept Videos

Loss of SIRT2 in cardiomyocytes reduces glycolytic flux via increased acetylation of glycolytic enzymes.

Lowering Cardiac Branched-Chain Keto Acid Levels Enhances Cardiac Glucose Oxidation and Cardiac Efficiency via Enhancing Mitochondrial Insulin Signaling in Heart Failure.

Casein Kinase 2α Ablation Confers Protection Against Metabolic Dysfunction-Associated Steatotic Liver Disease: Role of FUN14 Domain Containing 1-Dependent Regulation of Mitophagy and Ferroptosis.

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC.

Sweeteners: erythritol, xylitol and cardiovascular risk-friend or foe?

Alterations of myocardial ketone metabolism in heart failure with preserved ejection fraction (HFpEF).

Mechanosensitive Endothelial METTL7A Regulates Internal m7G mRNA Methylation and Protects Against Atherosclerosis.

YAP Promotes Microtubule Growth to Facilitate Sarcomere Disassembly in Adult Cardiomyocytes.

The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning.

ABHD11-Mediated mtDNA Transcription Restored Mitochondrial Function to Attenuate Cardiomyocyte Ferroptosis After Myocardial Infarction.

Opportunistic Screening for Chagas Disease Using an Artificial Intelligence-Enabled ECG: Prospective Evaluation of Feasibility and Diagnostic Accuracy.

The Postcardiac Arrest Inflammatory Response: Mechanisms and Therapeutic Targets.

Activation of a TFAM-Dependent Mitochondrial Translational Axis Drives Oxidative Metabolism in Grade 2 Meningiomas.

Targeted inhibition of the BDNF/AKT/mTOR pathway in the inferior colliculus ameliorates salicylate-induced tinnitus in rats.

Diaphragmatic Eventration Masquerading as Lobar Collapse in Severe ABPA.

Improvement of Severe Volume Dependent Airway Closure With Tezepelumab: A Case Report.

Related Experiment Videos

Metabolic modulation: a means to mend a broken heart

Related Concept Videos

Related Articles