Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Piezoelectric ceramic--a novel material for bone replacement].

L Chen¹, Z Chen, M Zhang

¹Department of Biomaterials, West China College of Stomatology, Sichuan University, Chengdu 610041.

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi

|January 17, 2002

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Covalent linkage between proteins of the inter-alpha-inhibitor family and hyaluronic acid is mediated by a factor produced by granulosa cells.

The Journal of biological chemistry·1996

Same author

Two-tone rate suppression boundaries of cochlear ganglion neurons in normal chickens.

The Journal of the Acoustical Society of America·1996

Same author

Greater ozone-induced inflammatory responses in subjects with asthma.

American journal of respiratory and critical care medicine·1996

Same author

Use of combinatorial peptide libraries to construct functional mimics of tumor epitopes recognized by MHC class I-restricted cytolytic T lymphocytes.

The Journal of experimental medicine·1996

Same author

Recurrent transition at a CG dinucleotide in exon 12 of COL2A1 produces kniest dysplasia with abnormal RNA splicing by chondrocytes and lymphoblasts and interruption of the triple helix of type II collagen.

Annals of the New York Academy of Sciences·1996

Same author

Inogatran, a novel direct low molecular weight thrombin inhibitor, given with, but not after, tissue-plasminogen activator, improves thrombolysis.

The Journal of pharmacology and experimental therapeutics·1996

This study demonstrates that piezoelectric ceramics are biocompatible bone graft materials. They support cell growth, integrate with bone, and can direct new bone formation, suggesting potential for bone replacement applications.

Area of Science:

Biomaterials Science
Biomedical Engineering
Tissue Engineering

Context:

Natural bone exhibits piezoelectric properties, influencing bone regeneration.
Developing synthetic materials that mimic bone's electrical and mechanical characteristics is crucial for effective bone defect repair.
Evaluating the comprehensive biocompatibility of novel materials is essential before clinical application.

Purpose:

To assess the biocompatibility of a piezoelectric ceramic for potential use as a bone graft substitute.
To investigate the material's interactions with bone tissue across cytocompatibility, tissue-compatibility, mechanical compatibility, and electro-compatibility.

Summary:

The piezoelectric ceramic showed no harm to L929 cell morphology or proliferation (cytocompatibility).

Related Experiment Videos

Excellent osteal integration was observed between the ceramic and bone tissue (tissue-compatibility).

The ceramic's mechanical properties are suitable for bone replacement, and its piezoelectric nature can guide osseous tissue growth directionally.

Impact:

This piezoelectric ceramic shows promise as a novel biomaterial for bone replacement therapies.
The findings support the development of advanced piezoelectric materials for guided bone regeneration.
Potential to improve outcomes in orthopedic and dental bone defect treatments.