Related Experiment Video
Updated: Jul 20, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
Published on: February 16, 2018
Lasonolide A: structural revision and synthesis of the unnatural (-)-enantiomer
Eun Lee1, Ho Young Song, Jung Won Kang
1School of Chemistry and Molecular Engineering, Seoul National University, Seoul 151-747, Korea.
Abstract:
Total synthesis of the unnatural (-)-enantiomer of lasonolide A was achieved starting from ethyl l-malate. The two tetrahydropyranyl fragments were prepared stereoselectively via radical cyclization reactions of beta-alkoxyacrylates. The full structure of natural lasonolide A was determined unequivocally.
More Related Videos
10:17Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
11:04Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Related Concept Videos
Naming Enantiomers
Prochirality
SN2 Reaction: Stereochemistry
If the substrate is an achiral molecule at the α-carbon, the inversion of configuration is not observed.
Diels–Alder Reaction Forming Cyclic Products: Stereochemistry
Stereochemical Effects of Enolization
Alkylation of β-Diester Enolates: Malonic Ester Synthesis