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Antibiotic-induced recurring interstitial nephritis
Abdullah Sakarcan1, Roxanne Marcille, James Stallworth
1Department of Pediatrics, Division of Pediatric Nephrology, University of South Carolina School of Medicine, Columbia, SC 29203, USA. abdullahsakarcan@hotmail.com
Pediatric Nephrology (Berlin, Germany)
|January 17, 2002
Abstract:
Acute interstitial nephritis (AIN) is often induced by drug therapy and accounts for 1%-3% of adult cases of renal failure. A 13-year-old white female with cystic fibrosis developed two episodes of biopsy proven AIN following antibiotic use over a 5-year period. The first episode resolved with pulse steroid therapy and the second resolved without intervention. Steroid therapy may play a role in aborting subsequent AIN attacks.