Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An integrated web interface for large-scale characterization of sequence data.

K H Cheung1, A Kumar, M Snyder

  • 1Center for Medical Informatics, Yale University School of Medicine, 333 Cedar Street, P.O. Box 208009, New Haven, CT 06520-8009, USA. kei.cheung@yale.edu

Functional & Integrative Genomics
|January 17, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A simple radioassay for detection of antithyroglobulin autoantibodies.

The Indian journal of medical research·1992
Same author

An immunoradiometric assay for measurement of serum thyroglobulin.

The Indian journal of medical research·1992
Same author

Modification of radiosensitivity by the so-called tissue recovery stimulator. I. Radiosensitizing effects of solcoseryl.

Journal of radiation research·1992
Same author

Postnatal laminar development of cholinergic receptors, protein kinase C and dihydropyridine-sensitive calcium antagonist binding in rat visual cortex. Effect of visual deprivation.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience·1992
Same author

Cerebral glucose metabolic rates after 30 and 45 minute acquisitions: a comparative study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1992
Same author

Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography.

Analytical biochemistry·1992
Same journal

Positive regulatory role of EuWRKY1 in the biosynthesis of Eucommia ulmoides rubber.

Functional & integrative genomics·2026
Same journal

Environmental enrichment modulates, but does not normalize, aging-associated immune transcriptional programs after ischemic stroke.

Functional & integrative genomics·2026
Same journal

A hypoxia-responsive migrasome-related lncRNA signature predicts prognosis and suggests the MSC-AS1/ITGA5 axis as a potential therapeutic target in head and neck squamous cell carcinoma.

Functional & integrative genomics·2026
Same journal

Genome-wide exploration of biosynthetic gene clusters and their association with virulence in the entomopathogenic fungus Beauveria.

Functional & integrative genomics·2026
Same journal

Single-cell transcriptomic analysis identifies a tumor-enriched GIMAP7⁺ CD4⁺ naïve T cell population with a unique immunoregulatory state in lung adenocarcinoma.

Functional & integrative genomics·2026
Same journal

Integrating artificial intelligence and multi-omics data for precision oncology in endometrial cancer: a narrative review.

Functional & integrative genomics·2026
See all related articles

Analyzing large genomic datasets is challenging due to complex, non-integrated software. We developed a web interface to streamline genomic analysis, improving data management and program integration for gene function studies.

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Large-scale genome projects generate substantial raw data requiring complex analysis pipelines.
  • Existing bioinformatics tools are often command-line driven, platform-dependent, and lack integration, hindering efficient data processing and navigation.

Purpose of the Study:

  • To address the challenges of analyzing large genomic datasets by developing an integrated, user-friendly platform.
  • To demonstrate a generalizable approach for integrating independent software programs into efficient genomic data processing protocols.

Main Methods:

  • Developed a platform-independent Web front end to integrate a suite of bioinformatics programs.
  • The interface facilitates launching analysis programs against multiple data file directories.

Related Experiment Videos

  • Enabled users to view, download, and upload processed data files, and track the processing status of datasets.

    • Main Results:

    • Successfully integrated multiple analysis programs for genomic data processing via a web interface.
    • The system efficiently handles large numbers of data files and tracks analysis status.
    • Demonstrated the identification of transposon insertion sites and disrupted open reading frames in Saccharomyces cerevisiae.

    Conclusions:

    • The developed Web interface significantly simplifies and enhances the analysis of large-scale genomic data.
    • This approach provides a generalizable solution for integrating disparate bioinformatics tools, improving efficiency in genomic research.
    • The platform facilitates gene function analysis through transposon mutagenesis studies in yeast.