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Genome scan for linkage to asthma using a linkage disequilibrium-lod score test

Y Jiang1, S L Slager, J Huang

  • 1Department of Statistics and Actuarial Science, 241 Schaeffer Hall, University of Iowa, Iowa City, IA 52242, USA.

Genetic Epidemiology
|January 17, 2002
PubMed

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...