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Related Experiment Videos

The "hot stroke" and transient vascular occlusions.

P R Yarnell, M P Earnest, B Sanders

    Stroke
    |September 1, 1975
    PubMed
    Summary

    Diagnosing transient vascular occlusions in stroke patients is possible. Increased radioisotopic flow to the affected hemisphere suggests embolism and warrants further investigation for an embolic source.

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    Area of Science:

    • Neurology
    • Nuclear Medicine
    • Radiology

    Background:

    • Middle cerebral artery (MCA) infarctions are a common cause of stroke.
    • Identifying the embolic source in stroke is crucial for patient management and prevention of recurrence.

    Observation:

    • Two patients with MCA infarctions exhibited "hot stroke" criteria on technetium-99m pertechnetate gamma camera studies.
    • Radioisotopic findings showed paradoxical increased flow to the affected hemisphere.

    Findings:

    • Serial angiography revealed transient occlusions in multiple MCA branches, which later became patent.
    • These angiographic findings, coupled with increased radioisotopic flow, suggest embolic events.
    • The "hot stroke" sign may indicate transient vascular occlusions within days to weeks post-infarction.

    Implications:

    • This study proposes a non-invasive method to diagnose transient vascular occlusions using radioisotopic imaging.
    • The "hot stroke" sign can prompt a search for embolic sources in stroke patients.
    • Early identification of embolic sources can improve stroke treatment strategies and reduce secondary events.

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