Unruptured intracranial aneurysms: a review

Area of Science:

• Neurology
• Neurosurgery
• Radiology

Background:

• Unruptured intracranial aneurysms (UIAs) present complex management challenges.
• Treatment decisions for UIAs necessitate integrating diverse clinical information.

Purpose of the Study:

• To review pathological, radiological, and clinical data relevant to unruptured intracranial aneurysms.
• To inform treatment decision-making for UIAs.

Main Methods:

• Comprehensive literature review of UIA pathology, radiology, and clinical presentations.
• Classification of UIAs based on incidental, multiple, or symptomatic status.
• Comparison of UIA profiles with ruptured lesions and autopsy findings.

Main Results:

• UIAs with profiles similar to ruptured aneurysms may warrant treatment at smaller sizes.
• Surgeon/institution track record and patient factors are crucial in decision-making.
• Periodic radiological assessment is advised for non-treated UIAs.

Conclusions:

• Aneurysm diameter is important but not the sole determinant for UIA treatment.
• Holistic assessment of UIA characteristics is essential for optimal patient management.