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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

18
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
18
Allergic Reactions02:06

Allergic Reactions

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Overview
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Antibody Structure01:10

Antibody Structure

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Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Allergic Drug Reactions01:27

Allergic Drug Reactions

1.5K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.5K

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Drug-induced enterocolitis syndrome (DIES) in a 10-year-old girl.

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[Persistent coughs in children and adolescents].

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[Solid food introduction and allergic risk].

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[Apparent life-threatening events due to cow's milk allergy in infants].

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Related Experiment Video

Updated: Feb 17, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

[Allergy examination in the child].

E Bidat1

  • 1Service de Pédiatrie-Hôpital Ambroise Paré-92104 Boulogne.

Allergie Et Immunologie
|January 19, 2002
PubMed
Summary

Allergies affect over 20% of children, often presenting with various symptoms. A clinical approach is key to diagnosing allergies, distinguishing them from other conditions with similar presentations.

Area of Science:

  • Pediatric Allergy
  • Immunology
  • Clinical Diagnosis

Context:

  • Allergic conditions are prevalent, impacting over 20% of children and frequently complicating medical consultations.
  • Allergic reactions often coexist with other etiological factors, necessitating a comprehensive diagnostic approach.
  • Recurrent symptoms warrant thorough assessment to differentiate allergic components from other potential diagnoses.

Purpose:

  • To outline a strategic approach for the efficient and cost-effective diagnosis of allergy-related symptoms.
  • To emphasize the primary role of clinical evaluation in allergy investigation.
  • To clarify the distinction between allergen sensitization and clinical allergy.

Summary:

  • Allergy investigation prioritizes clinical assessment, with complementary tests serving a confirmatory role for allergen-specific IgE.

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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

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Last Updated: Feb 17, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

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  • Sensitization involves IgE production without immediate symptoms, while clinical allergy manifests with symptoms upon re-exposure.
  • A structured diagnostic strategy, aligned with established medical guidelines, is crucial for timely and accurate allergy diagnosis.

    • Impact:

    • Facilitates earlier and more accurate diagnosis of pediatric allergies.
    • Reduces unnecessary diagnostic procedures and associated costs.
    • Improves patient management by identifying the true etiological factors of recurrent symptoms.