[A clinical study on solute removal index as an index to quantitate the adequacy of hemodialysis]
Related Experiment Video
Updated: Aug 11, 2026

Custom-made Microdialysis Probe Design
Published on: July 21, 2015
1Department of Nephrology, Affiliated Beijing Friendship Hospital of Capital University of Medical Science, Beijing 100050.
Objective:
In order to find a proper hemodialysis dosage and improve the life quality of the patients undergoing hemodialysis.
Methods:
A clinical study of solute removal index (SRI) was performed in 20 stable maintenance hemodialysis patients. Plasma BUN level was tested before and at the end of hemodialysis as well as 1 hr post-hemodialysis. Urea regeneration rate (G), protein catabolic rate (PCR), solute removal amount (R) and SRI were calculated by double-pool urea kinetic model.
Results:
It is shown that urea rebound rate was (18.50 +/- 3.35)% 1 hr post-hemodialysis, R was (13.82 +/- 5.48)g, G was (4.85 +/- 1.39)g, PCR was (0.94 +/- 0.29)g x kg(-1) x d(-1), SRI was (71.33 +/- 6.80)% respectively.
Conclusion:
The results indicated that SRI is a better index to quantitate the adequacy of hemodialysis.
Related Concept Videos
Dialysis
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Hemodialysis I: Introduction

