Related Experiment Video
Updated: Aug 17, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Pathological changes and protection of hypothalamus in pediatric craniopharyngioma]
Objective:
To understand the pathological changes of pediatric craniopharyngiomas so as to analyze its diagnosis, operative strategy and to prevent the damage of hypothalamus.
Methods:
189 cases of pediatric craniopharyngiomas treated from 1990 to 1998 were reviewed and analyzed via their CT, MRI, and surgery.
Results:
187 cases (98.9%) were cystic tumors, including 176 with calcification (93.1%); two cases were solid tumors (1.1%), and calcification occurred in only one. A gliosis layer between the wall of tumor and the hypothalamus was seen.
Conclusion:
Cystic change and calcification are the pathological features of pediatric craniopharyngiomas. There are some special relations between the tumors and stalk. These are the bases for total removal of pediatric craniopharyngiomas.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Cerebral Edema ll: Pathophysiology
Cytotoxic Edema: Pathophysiology

