Related Experiment Videos
[The relationship between prostate cancer and multi-estimating results of prostate-specific antigen]
1Department of Urology, General Hospital, Bengang Iron & Steel Co, Benxi 117000, China.
Objective:
To analyze the relationship between prostate cancer and multi-estimating results of prostate-specific antigen (PSA).
Methods:
In accordance with the results of 76 cases checked on PSA over 2 years, univariate and multivariate analysis were performed in prostate cancer connected with PSA, PSA density (PSAD), PSA velocity (PSAV), age-specific PSA (PSA-age), and free to total PSA ratio (fPSA/tPSA) by means of t test, Chi-square test, and logistic regression.
Results:
Of the 76 cases observed, 16 were diagnosed with prostate cancer. By univariate analysis, all factors of PSA, PSAD, PSAV, age-PSA and fPSA/t PSA showed conspicuous correlations with prostate cancer. However, in multivariate analysis, only did fPSA/t PSA (P = 0.006) with regressive ratio being positive number and PSAD (P = 0.018) with regressive ratio being negative number reveal statistical differences with prostate cancer.
Conclusion:
In multi-estimating results of PSA, fPSA/t PSA as a risk factor and PSAD as a protective factor were more correspondant with the principle for screen test of prostate cancer.