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Minimal change glomerulonephritis following a wasp sting
1Department of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. fzaman@lsuhsc.edu
American Journal of Nephrology
|January 19, 2002
Summary
A wasp sting triggered nephrotic syndrome in a young male, diagnosed as minimal change glomerulonephritis. Treatment with prednisone resolved proteinuria, with no relapse, highlighting a rare but treatable association.
Area of Science:
- Nephrology
- Toxicology
- Immunology
Background:
- Nephrotic syndrome is a kidney disorder characterized by heavy protein in the urine.
- Minimal change glomerulonephritis is a common cause of nephrotic syndrome in children and adults.
- Insect stings, particularly Hymenoptera, have been anecdotally linked to various systemic reactions.
Observation:
- A young male presented with nephrotic syndrome following a wasp sting.
- Renal biopsy confirmed minimal change glomerulonephritis.
- The patient exhibited significant proteinuria.
Findings:
- Treatment with oral prednisone led to complete resolution of proteinuria.
- The patient remained in good health with normal renal function after gradual corticosteroid tapering.
- No relapse of nephrotic syndrome was observed.
Implications:
- This case suggests a potential causal link between wasp stings and minimal change glomerulonephritis.
- It underscores the importance of considering environmental triggers in nephrotic syndrome etiology.
- Early diagnosis and corticosteroid treatment appear effective for wasp sting-associated nephrotic syndrome.
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