Related Experiment Video
Updated: Feb 15, 2026

07:10
A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury
Published on: March 31, 2023
1.6K
Mortality and morbidity from intra-aortic balloon pumps. Risk analysis
M Meco1, G Gramegna, A Yassini
1Division of Cardiac Surgery, Malan Center, S. Ambrogio Clinical Institute, Milan, Italy. mecoma@inwind.it
The Journal of Cardiovascular Surgery
|January 23, 2002
Summary
Postoperative intra-aortic balloon pump (IABP) support is associated with high mortality (57.8%) and complications like limb ischemia and renal insufficiency. Key predictors of mortality include IABP timing and thrombocytopenia.
Area of Science:
- Cardiology
- Vascular Surgery
- Critical Care Medicine
Background:
- Postoperative intra-aortic balloon pump (IABP) support is utilized in high-risk cardiac surgery patients.
- Assessing the incidence and predictors of mortality and morbidity following IABP use is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the incidence of mortality and morbidity in patients requiring postoperative intra-aortic balloon pump (IABP) support.
- To identify independent predictors of mortality, vascular complications, and renal insufficiency after IABP insertion.
Main Methods:
- Retrospective analysis of 116 patients who received postoperative IABP support.
- Statistical analysis including multivariate analysis to identify significant predictors.
Main Results:
- Mortality rate was 57.8%. Major vascular complications occurred in 16.3% (limb ischemia, aortic dissection, mesenteric infarction).
- Minor vascular complications (bleeding, infection) occurred in 25.8%. Renal insufficiency affected 51.7%, with 40% requiring dialysis.
- Neurological complications (10.3%), thrombocytopenia (11.2%), and sepsis (4.3%) were also observed.
Conclusions:
- IABP insertion incidence was 1.5% in this institution, with a mortality rate comparable to other studies.
- Independent predictors of mortality include IABP timing, thrombocytopenia, peripheral vascular disease, and redo intervention.
- Predictors for limb ischemia include female sex, diabetes, smoking, and antiplatelet use. Low ejection fraction and no dobutamine predict renal insufficiency.
Related Concept Videos
ATP Driven Pumps III: V-type Pumps
4.9K
V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
4.9K
ATP Driven Pumps II: P-type Pumps
6.5K
The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
6.5K
Relative Risk
2.2K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K
Pumped Concrete
401
Concrete in large quantities can be pumped across long distances for placing in inaccessible sites. This system comprises a hopper that receives concrete from a mixer, a pump to propel the concrete, and pipelines that facilitate its delivery.
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
For direct-acting pumps, the concrete enters the pump via the inlet valve under the action of gravity and suction created by the movement of the piston. This concrete is then forced into the pipeline and out through the outlet valve by the forward movement...
401
Refrigerators and Heat Pumps
3.1K
Refrigerators or heat pumps are heat engines operating in a reverse direction. For a refrigerator, the focus is on removing heat from a specific area, whereas, for a heat pump, the focus is on dumping heat into one particular area. A refrigerator (or heat pump) absorbs heat Qc from the cold reservoir at Kelvin temperature Tc and discards heat Qh to the hot reservoir at Kelvin temperature Th, while work W is done on the engine’s working substance.
A household refrigerator removes heat from...
A household refrigerator removes heat from...
3.1K
Factors Affecting the Risk of Infection
13.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.9K

