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Updated: Oct 2, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
[Management of patients with alcohol problems: how effective? Several response factors based on a review of the
B Graz1, J Cornuz, J B Daeppen
1Institut Universitaire de Médecine Sociale et Préventive, rue du Bugnon 17, 1005 Lausanne. Bertrand.Graz@inst.hospvd.ch
Abstract:
What do we know about the effectiveness of various treatments of alcoholism? This review of literature shows that lack--or weaknesses--of published studies make it impossible to draw definite conclusions. Rigorous controlled studies show high rates of spontaneous remission and important uncertainties about specialised treatments of alcoholism. However, except for severe dependence that may well require a different approach, brief interventions conducted by non-specialists have proved highly effective for at-risk alcohol drinkers: based on minimal medical advice, they increase the chances of lowering alcohol consumption. General practitioners may thus represent on important link in the therapeutic chain.
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