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Microbial killing activity of peracetic acid

V Thamlikitkul1, S Trakulsomboon, S Louisirirotchanakul

  • 1Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|January 24, 2002
PubMed

Insights

Peracetic acid (0.26% w/v) demonstrated potent in vitro antimicrobial activity. This disinfectant effectively killed a broad spectrum of bacteria, including MRSA, and viruses within a 10-minute exposure period.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Healthcare-associated infections pose a significant challenge.
  • Effective disinfectants are crucial for infection control.
  • Peracetic acid is a widely used chemical disinfectant.

Purpose of the Study:

  • To evaluate the in vitro antimicrobial efficacy of peracetic acid.
  • To determine the killing activity against a diverse range of pathogens.

Main Methods:

  • In vitro testing of peracetic acid at 0.26% w/v.
  • Exposure of various microorganisms and viruses to the disinfectant for 10 minutes.

Main Results:

  • Peracetic acid exhibited broad-spectrum killing activity.
  • Complete eradication of tested bacteria, including Escherichia coli, Pseudomonas aeruginosa, and MRSA.
  • Effective inactivation of Bacillus subtilis spores, Mycobacterium tuberculosis, and human immunodeficiency virus type I.

Conclusions:

  • Peracetic acid (0.26% w/v) is a highly effective disinfectant against a wide array of microorganisms and viruses.
  • The disinfectant shows promise for use in infection control settings.
  • Rapid and comprehensive killing activity supports its application in sterilization and disinfection protocols.

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