Related Experiment Video
Updated: Jul 17, 2026
08:34
Isolation of Atrial Myocytes from Adult Mice
Published on: July 25, 2019
Summary
Familial atrial myxomas were diagnosed in two siblings. Echocardiography is effective for diagnosing atrial myxoma, detecting recurrence, and screening family members.
Area of Science:
- Cardiology
- Genetics
- Oncology
Background:
- Atrial myxomas are rare tumors, typically benign, that can cause significant cardiovascular complications.
- While often sporadic, familial clustering of atrial myxomas suggests a possible genetic predisposition.
Purpose of the Study:
- To report a rare case of familial atrial myxomas in siblings.
- To highlight the diagnostic utility of echocardiography in identifying and monitoring atrial myxomas and related conditions.
Main Methods:
- Case report detailing the diagnosis and successful surgical excision of atrial myxomas in two siblings.
- Utilized echocardiography for initial diagnosis, tumor characterization, and surveillance.
Main Results:
- Two siblings, 14 years apart, were diagnosed with atrial myxomas (right and left atria).
- The sister also presented with peripheral cerebral and coronary aneurysms.
- Both patients underwent successful tumor excision.
Conclusions:
- The occurrence of atrial myxomas in siblings supports the hypothesis of a familial or genetic component.
- Echocardiography is a crucial tool for the diagnosis, recurrence detection, and family screening of atrial myxomas.
More Related Videos
Related Concept Videos
01:27Mitral Valve Prolapse I: Introduction
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
01:25Cardiomyopathy I: Introduction and Classification
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
01:30Cardiomyopathy II: Dilated Cardiomyopathy
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...