Related Experiment Video
Updated: Aug 17, 2026

Flash Photolysis of Caged Compounds in the Cilia of Olfactory Sensory Neurons
Published on: October 29, 2011
Effects of noise on the off rate of Ca(2+) binding proteins in a coupled biochemical cell system
1Department of Chemical Physics, University of Science and Technology of China, Hefei, Anhui 230026, PR China.
Abstract:
We investigated numerically the kinetic properties of calcium binding proteins by using a three-calcium store model and discussed the response of a two-way coupled biochemical cell system, whose subsystems were coupled via diffusion-like cytosolic calcium transfer through gap junctions, to the external stimulation. When we used noise to modulate the off rate of the Ca(2+) binding proteins in simulation, an SR-like phenomenon of synchronous oscillations is observed. In addition, the interaction involving noise, coupling and the dynamics of Ca(2+) binding proteins is discussed.
More Related Videos
14:09Fluorescence Biomembrane Force Probe: Concurrent Quantitation of Receptor-ligand Kinetics and Binding-induced Intracellular Signaling on a Single Cell
Published on: August 4, 2015
09:07Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
Published on: February 18, 2020
Related Concept Videos
Amplifying Signals via Second Messengers
G-Protein Gated Ion Channels
Sensory organs,...
Feedback Regulation of Calcium Concentration
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
Calmodulin-dependent Signaling
The Ca2+-CaM complex does not have enzymatic activity by itself. Instead, the complex binds downstream target proteins, including membrane proteins or enzymes,...
Ligand-Gated Ion Channel Receptor: Gating Mechanism
Relaxation of Skeletal Muscles
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open.