Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis: immunologic aspects.

R P Lisak

    Annals of Clinical and Laboratory Science
    |September 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Multiple sclerosis (MS) is a central nervous system demyelinating disease. Its pathogenesis involves complex interactions between autoimmunity, immunogenetics, immunologic deficiency, and viral infection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Immunologic characterization of oligodendroglia.

    Neuroscience letters·2009
    Same author

    Predictors of well-being among significant others of persons with multiple sclerosis.

    Multiple sclerosis (Houndmills, Basingstoke, England)·2007
    Same author

    A prospective open-label study of glatiramer acetate: over a decade of continuous use in multiple sclerosis patients.

    Multiple sclerosis (Houndmills, Basingstoke, England)·2006
    Same author

    Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for immune-related molecules by central nervous system mixed glial cell cultures.

    Multiple sclerosis (Houndmills, Basingstoke, England)·2006
    Same author

    Neurologic consequence of delaying glatiramer acetate therapy for multiple sclerosis: 8-year data.

    Acta neurologica Scandinavica·2004
    Same author

    Glatiramer acetate (Copaxone): comparison of continuous versus delayed therapy in a six-year organized multiple sclerosis trial.

    Multiple sclerosis (Houndmills, Basingstoke, England)·2003
    Same journal

    <i>Letter to the Editor:</i> Detection of <i>Chlamydia trachomatis</i> Immunoglobulin E Antibody in Human Sera.

    Annals of clinical and laboratory science·2026
    Same journal

    Comparison of the DNA Preservation Capacity of Two Methods for the Long-Term Cryopreservation of Whole Blood Samples.

    Annals of clinical and laboratory science·2026
    Same journal

    Recurrence of Primary Mediastinal Yolk Sac Tumor with Brain Metastases: A Case Report and Literature Review.

    Annals of clinical and laboratory science·2026
    Same journal

    Intraoperative Imprint Cytology of <i>SMARCB1</i>-Mutant Desmoplastic Myxoid Tumor of the Pineal Region: A Case Report with Cytologic Differential Diagnosis and Literature Review.

    Annals of clinical and laboratory science·2026
    Same journal

    Bergenin Suppresses Glycolysis and Malignant Progression in Breast Cancer via the IGF1R-MAPK Signaling Pathway.

    Annals of clinical and laboratory science·2026
    Same journal

    Network Pharmacology and <i>in vitro</i> Experimental Validation Reveal the Anticancer Mechanisms of Cichoric Acid in Cervical Cancer.

    Annals of clinical and laboratory science·2026
    See all related articles

    Area of Science:

    • Neuroimmunology
    • Central Nervous System (CNS) Diseases

    Background:

    • Multiple sclerosis (MS) is a significant demyelinating disease affecting the CNS.
    • The exact etiology of MS remains unknown.
    • Current understanding suggests a multifactorial pathogenesis.

    Purpose of the Study:

    • To explore the complex interrelationships contributing to MS pathogenesis.
    • To review evidence linking autoimmunity, immunogenetics, immunologic deficiency, and viral infections to MS.

    Main Methods:

    • Literature review and evidence synthesis.
    • Discussion of existing research on MS etiology.
    • Analysis of immunologic and genetic factors.

    Main Results:

    • Pathogenesis of MS likely involves a combination of factors.

    Related Experiment Videos

  • Autoimmunity plays a crucial role in CNS demyelination.
  • Genetic predisposition and viral triggers are implicated.

    • Conclusions:

    • The development of MS is multifactorial, involving a complex interplay of genetic and environmental factors.
    • Further research into these interrelationships is essential for understanding MS.
    • Understanding these factors is key to developing effective MS treatments.