CD40L in autoimmunity and mucosally induced tolerance

Gut microbiome modulation by Veillonella ratti induces resistance to EAE pathogenesis via microbe-derived metabolites.

Experimental & molecular medicine·2026

Sublingual bivalent vaccination with PspA-C-CPE and Alcaligenes lipid A induces protective immunity against both Streptococcus pneumoniae and Clostridium perfringens.

Research square·2026

Granzyme K CD8⁺ T cells with tissue-resident features promote intestinal inflammation in patients with Crohn's disease.

Experimental & molecular medicine·2026

Apurinic/apyrimidinic endonuclease 1 prevents oxidative DNA damage in intestinal epithelial cells induced by genotoxic Escherichia coli NC101.

Redox biology·2026

Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity.

iScience·2026

Organoid phenotypic screening identified glycyrrhizin that confers protection against tumor necrosis factor-induced cell death.

Stem cell reports·2026

METTL1-mediated m7G modification of valine tRNAs drives metabolic adaptation in pancreatic ductal adenocarcinoma.

The Journal of clinical investigation·2026

Targeting the E3 ubiquitin ligase RNF10 ameliorates metabolic dysfunction-associated steatohepatitis in mice.

The Journal of clinical investigation·2026

Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors.

The Journal of clinical investigation·2026

Targeting KIT prevents brain arteriovenous malformations driven by ALK1-deficient angiogenic endothelial cells.

The Journal of clinical investigation·2026

Inhibiting menin attenuates high-fat diet-induced weight gain by limiting intestinal lipid absorption in mice.

The Journal of clinical investigation·2026

Endocardial transcription factor HAND2 orchestrates hypoxic and TGF-β signaling to modulate coronary artery formation.

The Journal of clinical investigation·2026

Gastrointestinal adverse events related to monoclonal antibodies: A comprehensive evaluation of data from the FDA Adverse Event Reporting System database.

Indian journal of pharmacology·2026

SWAP70 alleviates brain damage and neuroinflammation induced by cerebral ischemia-reperfusion by inhibiting autophagy.

General physiology and biophysics·2026

Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan.

Annals of medicine and surgery (2012)·2026

Association between serum anti-granulocyte-macrophage colony-stimulating factor autoantibodies and nintedanib-induced diarrhea in interstitial lung disease: a retrospective study.

Journal of thoracic disease·2026

Incidental mass found on screening colonoscopy.

Journal of surgical case reports·2026

Immunocyte phenotypes underlying the causal autoimmune features in narcolepsy type 1.

Journal of thoracic disease·2026

Related Experiment Videos

CD40L in autoimmunity and mucosally induced tolerance

Related Concept Videos

Gut microbiome modulation by Veillonella ratti induces resistance to EAE pathogenesis via microbe-derived metabolites.

Sublingual bivalent vaccination with PspA-C-CPE and Alcaligenes lipid A induces protective immunity against both Streptococcus pneumoniae and Clostridium perfringens.

Granzyme K CD8⁺ T cells with tissue-resident features promote intestinal inflammation in patients with Crohn's disease.

Apurinic/apyrimidinic endonuclease 1 prevents oxidative DNA damage in intestinal epithelial cells induced by genotoxic Escherichia coli NC101.

Newly isolated human-derived Lactobacillus fermentum strain stimulates IFN-γ-secreting CD8+ T cells for enhanced anti-cancer immunity.

Organoid phenotypic screening identified glycyrrhizin that confers protection against tumor necrosis factor-induced cell death.

METTL1-mediated m7G modification of valine tRNAs drives metabolic adaptation in pancreatic ductal adenocarcinoma.

Targeting the E3 ubiquitin ligase RNF10 ameliorates metabolic dysfunction-associated steatohepatitis in mice.

Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors.

Targeting KIT prevents brain arteriovenous malformations driven by ALK1-deficient angiogenic endothelial cells.

Inhibiting menin attenuates high-fat diet-induced weight gain by limiting intestinal lipid absorption in mice.

Endocardial transcription factor HAND2 orchestrates hypoxic and TGF-β signaling to modulate coronary artery formation.

Gastrointestinal adverse events related to monoclonal antibodies: A comprehensive evaluation of data from the FDA Adverse Event Reporting System database.

SWAP70 alleviates brain damage and neuroinflammation induced by cerebral ischemia-reperfusion by inhibiting autophagy.

Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan.

Association between serum anti-granulocyte-macrophage colony-stimulating factor autoantibodies and nintedanib-induced diarrhea in interstitial lung disease: a retrospective study.

Incidental mass found on screening colonoscopy.

Immunocyte phenotypes underlying the causal autoimmune features in narcolepsy type 1.

Related Experiment Videos

CD40L in autoimmunity and mucosally induced tolerance

Related Concept Videos

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