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Updated: Jul 6, 2026

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
Published on: February 15, 2021
Analysis of mammalian brain architecture
1Department of Cognitive Neurology, University of Tübingen, Germany. fahad.sultan@uni-tuebingen.de
Abstract:
The mammalian brain is composed of several distinct parts which show different growth in evolution. Clark, Mitra and Wang found that the two main cortices of the brain - the cerebral (neo-) cortex and the cerebellum - show very different growth, and that whereas the ratio of neocortex volume to total brain volume increases with evolution, the cerebellum occupies a constant proportion in different species. Here I compare the surface areas of the two cortices in different species and find that these show a simple proportionality. Contrary to the conclusion drawn by Clark et al., this linear dependence of size implies that the two major cortices increase their computational capacity in parallel, suggesting a functional dependence of the one upon the other.
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