Humoral immune response to allograft valve tissue pretreated with an antigen reduction process
R C Elkins1, M M Lane, S B Capps
1Section of Thoracic and Cardiovascular Surgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.
Seminars in Thoracic and Cardiovascular Surgery
|January 24, 2002
Abstract:
The humoral immune response to allograft heart valves as measured by PRA was absent in 52 of 57 (91%) patients at 1 month and was absent in 43 of 49 (88%) at 3 months in allograft valves treated with the SynerGraft process for antigen reduction. Short-term valve function is satisfactory. This may be associated with improved durability and long-term function.
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