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Updated: Oct 2, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Chemo-radiotherapy in locally advanced squamous cell carcinoma of the head and neck: factors affecting toxicity
Abstract:
Radiation and chemotherapy in the treatment of locally advanced squamous carcinoma of the head and neck can be used according to different strategies: concomitant, alternation, consecutive. The limiting acute toxicity is local with the radiosensitizing capacity of the drug and type of radiation fractionation being the predominant factors. Regimens providing more that 50% of complete responses are usually associate with a more than 40% incidence of severelocal reaction. More information is needed on late toxicity that influences the quality of life for these patients.
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