Related Experiment Videos
Efficacy of school urinary screening for membranoproliferative glomerulonephritis type 1
Y Kawasaki1, J Suzuki, R Nozawa
1Department of Pediatrics, Fukushima Medical University School of Medicine, Japan. tomo@fmu.ac.jp
Aims:
In order to evaluate the efficacy of a school urinary screening programme, children with membranoproliferative glomerulonephritis (MPGN) type 1 were studied.
Methods:
A total of 52 patients who had been diagnosed with MPGN type 1 from 1970 to 1997 were studied; 35 were identified after 1974 on screening (group S), and 17 were identified by presenting symptoms (group N), mostly before 1989.
Results:
Mean blood pressure was 89 mm Hg in group S and 104 mm Hg in group N; urinary protein excretion was 0.9 g/day in group S and 3.0 g/day in group N. Histopathological evidence of chronic changes was found in six group S and 15 group N patients. No patients in group S had renal insufficiency, but five patients in group N required regular haemodialysis.
Conclusions:
Results suggest that early identification by school urinary screening may enable early management and so improve prognosis of MPGN.