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Related Experiment Videos

Clinical experience with a mobile ocular perfusion pump.

R A Ralph, M G Doane, C H Dohlman

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |October 1, 1975
    PubMed
    Summary

    Continuous perfusion using a mobile pump effectively treated severe dry-eye symptoms in 12 patients. This innovative method offered significant relief, particularly after ocular surface injuries and surgeries.

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    Area of Science:

    • Ophthalmology
    • Biomedical Engineering

    Background:

    • Severe dry eye disease significantly impacts patient quality of life.
    • Conventional treatments may be insufficient for severe cases, including those following chemical burns or reconstructive surgeries.

    Purpose of the Study:

    • To evaluate the efficacy of continuous ocular surface fluid delivery using a mobile perfusion pump.
    • To assess the management of severe dry eye symptoms through constant perfusion.

    Main Methods:

    • A mobile perfusion pump was utilized for continuous fluid delivery to the ocular surface in 12 patients.
    • A total of 1,500 patient-days of perfusion were recorded, with one patient using the device for 2.5 years.
    • Various perfusion fluids were tested, including balanced salt solution, artificial tears, acetylcysteine, and serum/plasma.

    Main Results:

    • Continuous perfusion ameliorated severe dry-eye symptoms in all treated patients.
    • The mobile pump demonstrated value in managing dry eye, especially post-chemical burns, keratoplasty, or eyelid reconstruction.

    Conclusions:

    • Mobile perfusion pump delivery offers a valuable therapeutic option for severe dry eye.
    • This method provides sustained ocular surface hydration and symptom relief in challenging cases.

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