Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Clinicopathologic case reports: Optic nerve head metastasis.

B L Gallie, J E Graham, W S Hunter

Archives of Ophthalmology (Chicago, Ill. : 1960)

|October 1, 1975

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Political vaccine hesitancy: not new but growing problem.

Vaccine·2025

Same author

COVID-19 vaccination in pregnancy: How discrepant public health discourses shape responsibility for fetal health.

SSM. Qualitative research in health·2023

Same author

Neurological factors and Cesarean section in Australian women with epilepsy.

Epilepsy & behavior : E&B·2022

Same author

DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of the <i>RB1</i> gene promoter.

Epigenetics·2020

Same author

Do health care providers trust product monograph information regarding use of vaccines in pregnancy? A qualitative study.

Canada communicable disease report = Releve des maladies transmissibles au Canada·2019

Same author

Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register.

Seizure·2018

Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013

See all related articles

A rare case of lung carcinoma metastasizing directly to the cribriform plate, involving the retina and optic nerve, is presented. This direct spread suggests tumor emboli may lodge in specific cranial vasculature.

Area of Science:

Ophthalmology
Neurology
Oncology

Background:

Lung carcinoma is a common malignancy with diverse metastatic patterns.
Metastasis to the central nervous system can occur through various routes, including hematogenous spread.

Observation:

A unique case of direct tumor metastasis from lung carcinoma to the cribriform plate is detailed.
Ocular structures, including the retina and optic nerve, were affected by the metastasis.
No tumor invasion into the choroid was observed.

Findings:

The metastasis directly impacted the cribriform plate, a key anatomical structure at the base of the skull.
The involvement of the retina and optic nerve suggests a pathway through the ophthalmic vasculature.
The absence of choroidal invasion provides specific details about the metastatic spread pattern.

Related Experiment Videos

Implications:

This case highlights an unusual route of metastasis for lung carcinoma, emphasizing direct spread to the skull base.
Understanding this pathway can inform diagnostic imaging and treatment strategies for CNS metastases.
Further research into the vascular pathways of cranial metastasis is warranted.