[Changes in bone turnover under immobilization and remobilization. Animal experiments using 45Ca and tetracycline...

This paper presents an experimental study of rabbits immobilized in plaster of paris casts. By means of Tetracycline and 45Ca-labelling an immobilisation over 12 weeks showed a significant diminuition of bone formation. In the first stages of remobilisation the bone formation was found to be increased and became normally in a later stage. The lower dorsal spine was not sufficiently immobilized in our experiments. Therefore significant changes of bone turnover could not be observed.