Related Experiment Video
Updated: Aug 7, 2026

Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR
Published on: April 8, 2013
The structure and function of the helical heart and its buttress wrapping. VI. Geometric concepts of heart failure
G D Buckberg1, H C Coghlan, F Torrent-Guasp
1Department of Surgery, UCLA School of Medicine, Los Angeles, CA, USA.
Abstract:
The macroscopic basis for congestive heart failure is defined as conversion of a helical heart, whereby the apical loop fiber angle orientation that produces a 60% ejection fraction becomes more transverse to develop a spheric configuration. The geometric consequence is flattening of the apical loop architecture, so that the 15% shortening can produce only 30% ejection fraction. The fundamental shape change is alteration of normal relationships between the transverse basal loop and oblique apical loop, to make the apical loop become more basal through more transverse fiber orientation. These fundamental architectural changes are then used to evolve new procedures that restore a more normal, helical, ventricular architecture in ischemic and dilated cardiomyopathy. Direct intraoperative ventricular methods underlie surgical ventricular restoration or endoventricular surgical patch plasty procedures, the Batista procedure, and Pacopexy. These intraventricular objectives are then compared with external approaches without ventriculotomy (ie, reimplantation of cells, pericardial sleeve (acorn), surface radiofrequency ablation, and the myocor approaches). A survey of current direct ventricular clinical results that improve the underlying nondamaged muscle (ie, remote segment) is defined, and related to timing of procedures directed at rebuilding more normal ventricular shape before irreversible collagen and fibrosis develop. The overall intent is to convert the spheric heart into an elliptic configuration. Novel concepts are introduced to suggest an internal ventricular patch can be used as an intercavitary curtain, through covering nonscarred septal muscle (ie, normal but distended) to amplify left ventricular function through producing a more helical structure.
More Related Videos
Related Concept Videos
Anatomy of the Heart
Pathophysiology of Heart Failure
Chambers of the Heart
Deoxygenated blood from the body is received in the right...
Heart Valves
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Anatomy of the Heart
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
Heart Failure II: Pathophysiology

