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[Operative treatment of trigeminal neuralgia]
1Neurochirurgische Klinik, Gesundheitszentrum Evangelisches Stift St. Martin, Koblenz. hhgoerge@gzstift.de
Therapy:
Nowadays the theory of microvascular compression of the root entry zone of trigeminal nerve in case of trigeminal neuralgia is widely accepted. Pathological contacts between a-beta fibers and c-fibers are believed to be caused by an arterial compression in the root entry zone. It is these ephaptic contacts that have led to a logical therapeutic sequence of treatment by means of membrane stabilising agents like anticonvulsant drugs as carbamazepine, nonablative - and, in view of the pathophysiological concept, causal - surgery in form of microvascular decompression described by Jannetta and ablative operative methods, which are restricted to certain well-defined indications.
Additional Procedures:
Other and additional surgical procedures are of use only in cases of atypical facial pain or with therapy non-responders. Methods like Caudalis-DREZ-Lesion and specific techniques such as cervical superior ganglion infiltration with opioids are worth being mentioned.