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Pertussis vaccine in Japan
1Department of Pediatrics, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, 1197-1 Yazashi-cho, Asahi-ku, Yokohama 241-0811, Japan.
Summary
Acellular pertussis vaccines, combined with diphtheria and tetanus toxoids (APDT), have been used in Japan since 1981. This report reviews their clinical efficacy for immunization.
Area of Science:
- Immunology
- Vaccinology
- Public Health
Background:
- Acellular pertussis vaccines have been available in Japan since 1981.
- These vaccines are often administered in combination with diphtheria and tetanus toxoids (APDT vaccine).
Purpose of the Study:
- To review the clinical efficacy of acellular pertussis vaccines used in Japan.
- To provide an overview of acellular pertussis vaccine utilization and authorization in Japan.
Main Methods:
- Literature review of studies on acellular pertussis vaccines in Japan.
- Analysis of data on vaccine efficacy and usage patterns.
Main Results:
- Acellular pertussis vaccines are manufactured, authorized, and utilized in Japan.
- The report will summarize the clinical effectiveness of these vaccines for immunization purposes.
Conclusions:
- Acellular pertussis vaccines have a history of use in Japan.
- The clinical efficacy of these vaccines supports their role in immunization programs.