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Updated: Sep 1, 2026

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
Published on: March 18, 2014
Osteosarcoma of the distal radius treated by intraoperative extracorporeal irradiation
Tetsuji Yamamoto1, Toshihiro Akisue, Takashi Marui
1Department of Orthopaedic Surgery, Kobe University School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Abstract:
Osteoblastic osteosarcoma in the distal radius of a 50-year-old woman was treated by en bloc resection, intraoperative extracorporeal irradiation, and reimplantation. Twenty-three months after surgery finger function was good. No tumor recurrence or distant metastasis was found at the final follow-up examination. Intraoperative extracorporeal irradiation and reimplantation is an easy and convenient reconstructive surgical procedure after en bloc excision of a tumor in the distal radius. A biologic reconstruction with a precise anatomic fit is possible, and long-term endoprosthetic problems and maintenance of bone-banking facilities for allografts are avoided.

