[Incidence and risk factors for infections from hemodialysis catheters]

G Jean1

  • 1Centre de rein artificiel, Tassin La Demi-lune. Gjean14357@aol.com

Nephrologie
|January 29, 2002
PubMed

Insights

Hemodialysis catheter infections, including bacteremia and local infections, remain frequent despite advances. Staphylococcus aureus is a primary cause, with patient immunity and catheter type being significant factors.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Medical Device Infections

Background:

  • Catheter-related infections are a significant complication in hemodialysis patients.
  • Understanding risk factors is crucial for preventing serious outcomes like bacteremia and endocarditis.

Purpose of the Study:

  • To review and synthesize data on hemodialysis catheter-related infections since 1985.
  • To identify key microbial causes, risk factors, and complications associated with these infections.

Main Methods:

  • Systematic literature review of published data on hemodialysis catheter infections.
  • Analysis of reported prevalence, incidence, microbial agents, and risk factors.

Main Results:

  • Bacteremia prevalence: 1-20%; incidence: 0.72-9/1000 catheter-days. Local infection prevalence: 6-63%; incidence: 1-5/1000 catheter-days.
  • Staphylococcus aureus is the most common pathogen; skin colonization is a key risk factor.
  • Patient factors (impaired immunity, age, diabetes, iron overload) and catheter factors (duration, type) influence infection rates. Endocarditis and death are severe complications.

Conclusions:

  • Hemodialysis catheter infections persist as a major clinical challenge.
  • Multicenter studies are needed to evaluate care protocols and novel catheter materials for improved infection control.

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