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Asymptomatic bacteriuria in infants in eastern Turkey
H Caksen1, S Arslan, M Abuhandan
1Department of Pediatrics, Yüzüncü Yil University, Van, Turkey. huseyincaksen@hotmail.com
Insights
Asymptomatic bacteriuria (ABU) affects 12.3% of infants in Eastern Turkey, a higher rate than previously reported. This study highlights a link between ABU and pyuria in infants.
Area of Science:
- Pediatrics
- Infectious Diseases
- Urology
Background:
- Asymptomatic bacteriuria (ABU) is a common condition in infants.
- Previous studies have reported varying prevalence rates of ABU in pediatric populations.
- Understanding ABU prevalence is crucial for early detection and management of potential urinary tract infections.
Purpose of the Study:
- To determine the prevalence of ABU in infants in Eastern Turkey.
- To investigate the relationship between pyuria and ABU in this population.
- To compare ABU prevalence with existing literature and explore contributing factors.
Main Methods:
- A cohort of 146 infants aged 29 days to 15 months was studied.
- Urine samples were collected using sterile bags for bacterial culture.
- Pyuria was assessed in conjunction with urine culture results.
Main Results:
- The prevalence of ABU was found to be 12.3% based on the second urine culture.
- A significant positive correlation was observed between positive urine cultures and pyuria (p < 0.001).
- Malnutrition was present in 32.1% of infants, but did not significantly impact ABU prevalence.
Conclusions:
- The ABU prevalence in Eastern Turkey is higher than reported in other regions, potentially linked to socioeconomic factors and urine collection methods.
- Pyuria is a significant indicator associated with bacteriuria in infants.
- Further research using methods like suprapubic aspiration may be warranted to confirm findings.
Abstract:
In this study, the prevalence of asymptomatic bacteriuria (ABU) was investigated in the 146 infants without symptoms suggesting urinary tract infection, age ranged from 29 days to 15 months (mean 4.56 +/- 3.30 months). Our purpose was to determine the prevalence ofABU in infants living in Eastern Turkey and to define the relationship between pyuria and ABU in infants. Of 146 infants, 77 (52.7%) were males, and 69 (47.3%) were females. Although we would like to select randomized healthy infants for the study, 47 (32.1%) infants had a mild to severe malnutrition. While various microorganisms were cultured in 41 (28%) infants in the first urinary culture, only 18 (12.3%) infants had a positive culture in the second urinary culture. The prevalence of ABU was 12.3%. Although ABU prevalence was higher in the infants with malnutrition than those without malnutrition (14.8% 1 vs. 11.1%), there was not a difference between the groups (p>0.05). There was a positive relation between urinary culture positiveness and pyuria (p < 0.001). The prevalence of ABU was much higher (12.3%) than the literature data, which was probably related to very low socioeconomic status of our region where malnutrition and its related disorders are commonly seen. The high ratio might also be related to the method of urine collection, because we used sterile collecting bag, but not suprapubic aspiration method.