[Use of different parenterally administered amino acid solutions with healthy test subjects]

We studied the alterations in the pattern of free serum amino acids during continuous parenteral infusion of 4 different standardised L-amino acid solutions. Nearly for all amino acids, a dose-dependent steady state could be established, usually as early as 30 or 60 minutes after starting the infusion. Amino acid solutions that caused the smallest changes of the amino acid pattern in plasma during infusion produced always the smallest increase of total amino acid nitrogen and the greatest rate of amino acid transfer. So we conclude that these solutions are utilised most effectively.