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[Aging changes of alpha-amylase and lysozyme in normal parotid gland]
1Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology, Beijing 100081, China.
Objective:
To investigate the aging changes, the distribution and the content of alpha-amylase, lysozyme in the normal parotid glands.
Methods:
Fifty-one specimens of parotid glands with 4 different age groups were studied by immunohistochemical method. The intensity of staining of alpha-amylase, lysozyme was recorded in different age groups.
Results:
The staining positivity rate of alpha-amylase, lysozyme had striking differences in 4 different age groups and it gradually decreased along with the age increasing.
Conclusions:
There are differences among seous acinus which had similar shape and staining in HE slice. The characters of aging changes of alpha-amylase, lysozyme secreted by acinar and intercalated duct cells are conformity with the results of quantitative studies in histology.